Module 1 - Unlocking the Potential of TROP2-Targeted Therapy

This module discusses the role of TROP2-directed ADCs in treating patients with advanced NSCLC and adverse events associated with TROP2-directed ADCs.

Benjamin Levy, MD

Associate Professor
Johns Hopkins Sidney Kimmel Cancer Center
Washington, DC

Dr. Benjamin Levy is a thoracic medical oncologist and the clinical director of medical oncology for the Johns Hopkins Sidney Kimmel Cancer Center at Sibley Memorial Hospital, as well as an associate professor of oncology for Johns Hopkins University School of Medicine.

Dr. Levy is a physician scientist who is interested in innovative immunotherapeutic approaches for advanced stage lung cancer patients and biomarkers that help define those patients more likely to respond to such agents. He has an expertise in thoracic malignancies, including non-small cell lung cancer, small cell lung cancer and thymic malignancies, as well as head and neck cancer.

Alexander Spira, MD, PhD, FACP

Medical Oncologist
Director of VCS Research Institute
Director of VCS Phase 1 Program
Medical Director, US Oncology Lung Program
Fairfax, VA

Dr. Spira is a medical oncologist and is director of the Virginia Cancer Specialists Research Institute and the Phase I Trial Program, where he is actively involved in advancing medicine and offering targeted treatment options for patients. His research interests include immunotherapy, personalized medicine, GI, thoracic and lung cancer and sarcomas. Dr. Spira is co-chair of the US Oncology thoracic oncology committee, chair of the US Oncology research executive committee, and member of the US Oncology national policy board executive committee. He also serves on the cancer research committee of the American Society for Clinical Oncology. He is a faculty member at Johns Hopkins School of Medicine and serves as assistant professor of oncology.
1.
Enhance efficacy and patient response to combination treatment with emerging TROP2-directed ADCs in the first- and second-line treatment of patients with advanced/metastatic NSCLC
2.
Identify, mitigate, and manage adverse events associated with TROP2-directed therapies by monitoring both treatment response and patient quality of life