Credits Available: 5.0 AMA PRA Category 1 Credits

Description: The proposed activities will inform clinicians of recent evidence from clinical trials on the efficacy and safety of TROP2-directed antibody-drug conjugates (ADCs) in patients with progressive NSCLC, allowing them to quickly integrate new treatments into their practice when they become available. Clinicians will be updated on HER2 genomic alterations and apply appropriate testing methodologies per the National Comprehensive Cancer Network (NCCN) guidelines for NSCLC. Furthermore, participants will receive education on the successful management of NSCLC, including managing brain metastases, optimal HER2-targeted ADC dosing, and monitoring approaches for treatment-related adverse events (AEs). Finally, the proposed activities aim to educate participants on the importance of targeting HER3 and using HER3-directed ADCs in the management of NSCLC. The initiative will also provide information on the efficacy and safety of these ADCs based on clinical trial data, as well as strategies for recognizing and minimizing treatment-related AEs to enhance therapy adherence and improve patient outcomes.

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This program is intended for:
Target Professions: DO, MD, Nurse Practitioner, Physician Assistant
Target Specialties: Oncology

Michael Firstenberg

Maui Memorial Medical Center
Surgeon

Dr Michael S Firstenberg is a board-certified thoracic surgeon who specializes in adult cardiac surgery who actively practices at the Maui Memorial Medical Center in Hawaii, USA. Previously, he was Chief of Cardiothoracic and Vascular Surgery at the Medical Center of Aurora and Rose Hospitals. He currently holds appointments in the Colleges of Medicine and Graduate Studies at Northeast Ohio Medical University. He attended Case Western Reserve University Medical School, received his General Surgery training at University Hospitals in Cleveland, and completed Fellowships at The Ohio State University (Thoracic Surgery) and The Cleveland Clinic (Surgical Heart Failure). He is an active member of the Society of Thoracic Surgeons (STS), American Association of Thoracic Surgeons (AATS), the American College of Cardiology (ACC), and the American College of Academic International Medicine (ACAIM – for which he is a Founding Fellow and 2021-2022 President). He currently serves on several professional society committees. He is the author of well over 200 peer-reviewed manuscripts, abstracts, and book chapters. He has Edited several textbooks on topics ranging from Medical Leadership, Patient Safety, Endocarditis, COVID-19, and Extra-corporeal Membrane Oxygenation – all of which include topics that he has lectured on world-wide.